Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?

M. Mensink; M.K.C. Hesselink; Lars Borghouts; H.A. Keizer; E. Moonen-Kornips; G. Schaart; E.E. Blaak; P. Schrauwen

doi:10.1111/j.1463-1326.2006.00628.x

Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?

M. Mensink
, M.K.C. Hesselink
, Lars Borghouts
, H.A. Keizer
, E. Moonen-Kornips
, G. Schaart
, E.E. Blaak
, P. Schrauwen

Maastricht University

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › Wetenschappelijk › peer review

Samenvatting

Both exercise training and a lifestyle-intervention program increase UCP3 protein content inskeletal muscle of subjects with reduced glycaemic control, indicating a restoration towards normal UCP3 levels. These data support the idea that UCP3 has a role in the aetiology of type 2 diabetes mellitus

Originele taal	Engels
Pagina's (van-tot)	594-596
Tijdschrift	Diabetes, Obesity and Metabolism
Volume	9
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1111/j.1463-1326.2006.00628.x
Status	Gepubliceerd - jul 2007
Extern gepubliceerd	Ja

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Trefwoorden

type 2 diabetes
UCP3
insulin resistance
exercise
lifestyle intervention

Toegang tot document

10.1111/j.1463-1326.2006.00628.x

Citeer dit

Mensink, M., Hesselink, M. K. C., Borghouts, L., Keizer, H. A., Moonen-Kornips, E., Schaart, G., Blaak, E. E., & Schrauwen, P. (2007). Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis? Diabetes, Obesity and Metabolism, 9(4), 594-596. https://doi.org/10.1111/j.1463-1326.2006.00628.x

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title = "Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?",

abstract = "Both exercise training and a lifestyle-intervention program increase UCP3 protein content inskeletal muscle of subjects with reduced glycaemic control, indicating a restoration towards normal UCP3 levels. These data support the idea that UCP3 has a role in the aetiology of type 2 diabetes mellitus",

keywords = "type 2 diabetes, UCP3, insulin resistance, exercise, lifestyle intervention, type 2 diabetes, UCP3, insulin resistance, exercise, lifestyle intervention",

author = "M. Mensink and M.K.C. Hesselink and Lars Borghouts and H.A. Keizer and E. Moonen-Kornips and G. Schaart and E.E. Blaak and P. Schrauwen",

note = "Lectoraat Fysieke activiteit en gezondheid Lectoraat Fysieke activiteit en gezondheid",

year = "2007",

month = jul,

doi = "10.1111/j.1463-1326.2006.00628.x",

language = "English",

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Mensink, M, Hesselink, MKC, Borghouts, L, Keizer, HA, Moonen-Kornips, E, Schaart, G, Blaak, EE & Schrauwen, P 2007, 'Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?', Diabetes, Obesity and Metabolism, vol. 9, nr. 4, blz. 594-596. https://doi.org/10.1111/j.1463-1326.2006.00628.x

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T2 - implications for diabetes pathogenesis?

AU - Mensink, M.

AU - Hesselink, M.K.C.

AU - Borghouts, Lars

AU - Keizer, H.A.

AU - Moonen-Kornips, E.

AU - Schaart, G.

AU - Blaak, E.E.

AU - Schrauwen, P.

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KW - type 2 diabetes

KW - UCP3

KW - insulin resistance

KW - exercise

KW - lifestyle intervention

KW - type 2 diabetes

KW - UCP3

KW - insulin resistance

KW - exercise

KW - lifestyle intervention

U2 - 10.1111/j.1463-1326.2006.00628.x

DO - 10.1111/j.1463-1326.2006.00628.x

M3 - Article

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JO - Diabetes, Obesity and Metabolism

JF - Diabetes, Obesity and Metabolism

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ER -

Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?

Samenvatting

Duurzame ontwikkelingsdoelstellingen van de VN

Trefwoorden

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